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Introduction to Computational Biology

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Pharmacogenomics and personalised medicine [5 mins]
Pharmacogenomics in personalized medicine - Genetic variation in drug response - Genomic technology for tailored therapy - Clinical pharmacogenomics examples - Genetic biomarkers and predictive testing - Ethical challenges in implementation - Equity in pharmacogenomic testing - Routine healthcare integration

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Systemic sclerosis (SSc) [30 mins]
Systemic sclerosis pathogenesis - Scleroderma - Raynaud’s phenomenon - Calcinosis - Dilated nailfold capillaries - Telangiectasias - Interstitial lung disease - SSc classification - Pulmonary arterial hypertension - SSc renal crisis - Gastrointestinal involvement in SSc

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Neurons and glial cells [4 mins]
Nervous system structure - Roles of neurons and glial cells - Neuronal signal transmission - Glial cell functions and types - Neuron-glia interactions and health - Neurological disease relevance

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Pharmaceutical biotechnology [4 mins]
Pharmaceutical biotech advances - Biologic drug development - Large-scale production breakthroughs - Biologic manufacturing complexities - Biologic stability and immune challenges - Biosimilars and gene editing solutions - Regulatory landscape and impact

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Ethics and professionalism in healthcare [4 mins]
Healthcare ethics principles - Patient rights and confidentiality - Cultural sensitivity and professionalism - Handling ethical dilemmas - Teamwork and reflective practice - Professional development and codes - Public trust and patient well-being

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