EMOttawa Blog

There are few phrases in emergency medicine that generate as much discomfort as hearing, “Remember that patient you saw yesterday? They’re back.” Most of us immediately retrace the encounter in our minds, wondering whether something was missed or whether we should have managed things differently. That reaction is understandable because return visits can occasionally uncover [...

Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial.  Hernandez G, ANDROMEDA-SHOCK-2 Investigators for the ANDROMEDA Research Network JAMA. 2025 Oct 29:e2520402. doi: 10.1001/jama.2025.20402.   Editorial: Capillary Refill Time in Sepsis-Searching for the Holy Grail. M...

Acute Liver Failure (ALF) is rare, with an estimated incidence of 1–6 cases per million per year in Western countries¹². Despite its rarity, it carries significant morbidity and mortality¹. ALF most often affects previously healthy adults in their 30s; in North America, the median age is 38¹. Roughly 50% survive without transplant, 25% undergo transplant […]

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A Randomized Trial of Shared Decision-Making in Code Status Discussions Becker C, et al. NEJM Evid. 2025 May;4(5):EVIDoa2400422. doi: 10.1056/EVIDoa2400422.   Methodology: 3.5/5 Usefulness: 3.5/5   Question and Methods: This multi-centre cluster-RCT investigated the effect of didactic teaching, observation + feedback, and a decision aid tool vs. usual care...

Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial Xiong Y, Et al. Lancet. 2026 Feb 21;407(10530):763-772. doi: 10.1016/S0140-6736(25)02633-9.   Editorial: Intravenous tenecteplase for acute ischaemic stroke within 24 h due to b...